Alza E. Flow and Microreactonology in Medicinal Chem. 2022 torrent

Textbook in PDF format

Learn to master a powerful technology to enable a faster drug discovery workflow.
The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors—with integrated analysis of the resulting products—provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort.
In Flow and Microreactor Technology in Medicinal Chemistry , early adopters of this ground-breaking technology describe its current and potential uses in medicinal chemistry. Based on successful examples of the use of flow and microreactor synthesis for drug-like compounds, the book introduces current as well as emerging uses for automated synthesis in a drug discovery context.
Flow and Microreactor Technology in Medicinal Chemistry readers will also find:
Numerous case studies that address the most common applications of this technology in the day-to-day work of medicinal chemists.
How to integrate flow synthesis with drug discovery.
How to perform enantioselective reactions under continuous flow conditions.
Flow and Microreactor Technology in Medicinal Chemistry is a valuable practical reference for medicinal chemists, organic chemists, and natural products chemists, whether they are working in academia or in the pharmaceutical industry.
Flow Chemistry at the Extremes: Turning Complex Reactions into Scalable Processes
Automated Flow Chemistry Platforms
Flow Chemistry Opportunities for Drug Discovery
Flow Chemistry in Medicinal Chemistry: Applications to Bcr-Abl Kinase Inhibitors
Integrated Systems for Continuous Synthesis and Biological Screenings
Application of Continuous-Flow Processing in Multistep API and Drug Syntheses
Continuous-Flow Multistep Synthesis of Active Pharmaceutical Ingredients
Enantioselective (Bio)Catalysis in Continuous-flow as Efficient Tool for the Synthesis of Advanced Intermediates and Active Pharmaceutical Ingredients
Innovative Process Development of Pharmaceutical Intermediates Under Continuous-Flow System