Bhattacharjee A. The Oxford Handbook of Neuronal Ion Channels 2023 torrent

Textbook in PDF format

Neurons are excitable cells. They use ions and electrical signaling to talk to each to other and when they talk to each other, neurons control behavior. The Oxford Handbook of Neuronal Ion Channels is an accessible reference describing the nature and properties of ion channels in neurons. The book explains how ion channels open and close, how they can be selective for specific ions, and how they give rise to action potentials. Included are in-depth chapters discussing specific classes of ion channels: potassium channels, sodium channels, neurotransmitter-gated ion channels and other specialized channels. Throughout the handbook, important insight is provided on the contribution ion channels make to neuronal excitability and to synaptic transmission. The handbook goes further to discuss channelopathies, a group of human diseases such as epilepsy, pain and migraines that can be caused by ion channel dysfunction. For neuroscientists, biophysicists and neuropharmacologists, this
handbook is a valuable reference of ion channel biology and function.
Preface
Editor’s Bio
List of Contributors
Basic Principles
Excitable Membrane Properties of Neurons
Ion Channel Permeation and Selectivity
Gating of Ion Channels
Voltage-​Gated Channels
The Voltage-​Dependent K+​ Channel Family
Potassium Channel Mutations in Epilepsy
The Voltage-​Dependent Sodium Channel Family
Specialized Sodium Channels in Pain Transmission
Sodium Channelopathies of the Central Nervous System
Ligand-​Gated Channels
α-​Amino-​3-​Hydroxy-​5-​Methyl-​4-​Isoxazolepropionic Acid and Kainate Receptors
N-​Methyl-​D-​Aspartate Receptors
Nicotinic Acetylcholine Receptors
GABAA Receptor Physiology and Pharmacology
P2X Receptors
Large Conductance Potassium Channels in the Nervous System
Hyperpolarization-​Activated Cyclic Nucleotide–​Gated Channels
Other Channels
Tandem Pore Domain Potassium Channels
TRPC Channels—Insight from the Drosophila Light Sensitive Channels
Acid-​Sensing Ion Channels
TMEM16 Ca2+​ Activated Cl–​ Channels and CLC Chloride Channels and Transporters
Index