Xia Y. Bioinformatic and Statistical Analysis of Microbiome Data 2023 torrent

Textbook in PDF format

This unique book addresses the bioinformatic and statistical modelling and also the analysis of microbiome data using cutting-edge QIIME 2 and R software. It covers core analysis topics in both bioinformatics and statistics, which provides a complete workflow for microbiome data analysis: from raw sequencing reads to community analysis and statistical hypothesis testing. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of QIIME 2 and R for data analysis step-by-step. The data as well as QIIME 2 and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter so that these new methods can be readily applied in their own research.Bioinformatic and Statistical Analysis of Microbiome Data is an ideal book for advanced graduate students and researchers in the clinical, biomedical, agricultural, and environmental fields, as well as those studying bioinformatics, statistics, and big data analysis.
Introduction to QIIME 2
Introduction to R for Microbiome Data
Basic Data Processing in QIIME 2
Building Feature Table and Feature Representative Sequences from Raw Reads
Assigning Taxonomy, Building Phylogenetic Tree
Clustering Sequences into OTUs
OTU Methods in Numerical Taxonomy
Moving Beyond OTU Methods
Alpha Diversity
Beta Diversity Metrics and Ordination
Statistical Testing of Beta Diversity
Differential Abundance Analysis of Microbiome Data
Zero-Inflated Beta Models for Microbiome Data
Compositional Analysis of Microbiome Data
Linear Mixed-Effects Models for Longitudinal Microbiome Data
Introduction to Generalized Linear Mixed Models
Generalized Linear Mixed Models for Longitudinal Microbiome Data
Multivariate Longitudinal Microbiome Models