Colacino E. Mechanochemistry and Emerging Technologies...Chemical Manufact. 2023 torrent

Textbook in PDF format

This unique volume describes advances in the field of mechanochemistry, in particular the scaling up of mechanochemical processes. Scalable techniques employed to carry out solvent-free synthesis are evaluated. Comparability to continuous flow chemistry, the current industrial benchmark for continuous efficient chemical synthesis, is presented.The book concludes that mechanochemical synthesis can be scaled up into a continuous, sustainable process. It demonstrates that large-scale mechanochemistry can meet industrial demands, especially in the pharmaceutical industry. The case studies conducted on MOF Technologies and Deasyl demonstrate how mechanochemistry is employed on a pilot plant scale.
Features:
Mechanochemistry is rapidly developing as a multidisciplinary science on the borderline between chemistry, materials science and environmental science.
This unique text focuses on mechanochemistry with the ability to scale up and illustrates how mechanochemical synthesis is no longer an obstacle. This timely book highlights recent advancements describing what can be achieved in chemical synthesis.
Mechanochemistry enables the synthesis of multiple polymorphic crystalline forms in the production of drugs in the form of tablets or granules in capsules.
In Situ Monitoring of Mechanochemical Ball-Milling Reactions
The Thermodynamics and Kinetics of Mechanochemical Reactions: A Computational Approach
The Thermodynamics and Kinetics of Mechanochemical Reactions: An Experimental Approach
Life Cycle Assessment: A Tool for Sustainability Evaluation of Emerging Mechanochemical Process Engineering
Intellectual Property (IP) Strategy in Mechanochemistry
Mechanochemistry and Industry: Process Intensification and Beyond
On the Theory and Recent Developments in “Batch Mechanochemical Synthesis – Scale-Up”
Acoustic Synthesis (Solvent-Free) and Resonant Acoustic Mixing (RAM)
Sustainable Large-Scale Synthesis of Fine Chemicals, Active Pharmaceutical Ingredients and Biologically Active Compounds by Non-traditional Activation Methods and Biocatalysis
Eccentric Vibration Milling for Mechanochemical Synthesis: A Straightforward Route to Advanced Materials
Scalable Solutions for Continuous Manufacturing by Mechanochemical-Assisted Synthesis
Large-Scale Flow Chemistry
Sustainable Synthesis of API in Water in Industrial Setting