Svensson L. Viral Gastroenteritis. Molecular Epidemiology and Pathogenesis 2016 torrent

Textbook in PDF format

Viral Gastroenteritis: Molecular Epidemiology and Pathogenesis provides a comprehensive review of research on viruses causing acute gastroenteritis in infants and young children, including coverage of rotaviruses, human caliciviruses, astroviruses, enteric adenoviruses, and viruses causing gastroenteritis more rarely. Includes general chapters on gastrointestinal physiology and pathophysiology, gastrointestinal immune mechanisms, immunodeficiencies and host genetics influencing susceptibility to viral gastroenteritis, and therapeutic and preventative approaches.
The book also includes special sections on virus particle structures, replication cycles, pathogenesis, immunology, epidemiology, and preventative measures. This book covers both basic science and translational applications and is an appropriate resource for virologists, molecular biologists, epidemiologists, gastroenterologists, vaccinologists, and those with an interest in public health.
Features new approaches in diagnosis and characterization of viral gastroenteritis pathogensIncludes coverage of therapeutic and preventative methodsCovers recent advances in characterizing the molecular biology and immune responses of rotaviruses and norovirusesCovers both basic science and translational applications and is an appropriate resource for virologists, molecular biologists, epidemiologists, gastroenterologists, vaccinologists, and those with an interest in public health
Front matter
Copyright
Contributors
Introduction
Gastrointestinal Physiology and Pathophysiology,
Immunity in the Gut: Mechanisms and Functions
Immunodeficiencies: Significance for Gastrointestinal Disease
Therapy of Viral Gastroenteritis
Structure and Function of the Rotavirus Particle
Rotavirus Attachment, Internalization, and Vesicular Traffic
Rotavirus Replication and Reverse Genetics
Pleiotropic Properties of Rotavirus Nonstructural Protein 4 (NSP4) and Their Effects on Viral Replication and Pathogenesis
Rotavirus Replication: the Role of Lipid Droplets
Rotavirus Disease Mechanisms
Gnotobiotic Neonatal Pig Model of Rotavirus Infection and Disease
Innate Immune Responses to Rotavirus Infection
Human Acquired Immunity to Rotavirus Disease and Correlates of Protection
Molecular Epidemiology and Evolution of Rotaviruses
Rotavirus Vaccines and Vaccination
Structural Biology of Noroviruses
Calicivirus Replication and Reverse Genetics
Human Norovirus Receptors
Animal Models of Norovirus Infection
Molecular Epidemiology and Evolution of Noroviruses
Norovirus Vaccine Development
Studies of Astrovirus Structure–Function Relationships
Astrovirus Replication and Reverse Genetics
Molecular Epidemiology of Astroviruses
Enteric Viral Metagenomics
Interactions Between Enteric Viruses and the Gut Microbiota
Index