Harris R. Biochemistry and Cell Biology of Ageing Part III. 2023 torrent

Textbook in PDF format

This book provides a state-of-the-art overview of key areas of subcellular aging research in human cells.
The reader is introduced to the historical development and progress in biomedical aging research and learns, for example, about the role of microRNAs, circRNAs, mitochondria and extracellular vesicles in cellular senescence. The reader will also learn more about how gap junctions, the nuclear pore complex and the proteasome are affecting the ageing processes. In addition, novel therapeutic opportunities through modulation of cellular senescence are discussed.
The book follows on from Parts I and II of Biochemistry and Cell Biology of Ageing (Volumes 90 and 91 of the Subcellular Biochemistry book series) by covering interesting and significant biomedical ageing topics not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Preface
About og Editors
Introduction: Progression of the Science of Ageing
Chromatin Structure from Development to Ageing
The Nuclear Envelope in Ageing and Progeria
Mitochondrial DNA Mutations and Ageing
The Proteasome and Ageing
Gap Junctions and Ageing
Cellular Senescence and Ageing
Therapeutic Opportunities Presented by Modulation of Cellular Senescence
Ageing at Molecular Level: Role of MicroRNAs
CircRNA and Ageing
Extracellular Vesicles and Cellular Ageing
Fibrinogen, Coagulation, and Ageing
An Insight into Platelets at Older Age: Cellular and Clinical Perspectives
Ageing Skeletal Muscle: The Ubiquitous Muscle Stem Cell
Age-Related Changes in Central Nervous System 5-Hydroxytryptamine Signalling and Its Potential Effects on the Regulation o...
Systems Biology of Ageing