Textbook of Drug Design and Discovery (5th Ed)(gnv64) torrent

Textbook of Drug Design and Discovery (5th Ed)
by Kristian Stromgaard and Povl Krogsgaard-Larsen
CRC Press | August 2016 | ISBN-10: 1498702783 | ePUB | 34.9 mb
https://www.amazon.com/Textbook-Drug-Design-Discovery-Fifth/dp/1498702783

Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects.
The first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery.
The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors.
The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.

About the Authors
Kristian Strømgaard is a professor of chemical biology in the Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, at the University of Copenhagen and a director of the Center for Biopharmaceuticals, Copenhagen, Denmark.
Povl Krogsgaard-Larsen is a professor of medicinal chemistry in the Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, at the University of Copenhagen, Copenhagen, Denmark.

CONTENTS
Preface
Editors
Contributors
Chapter 1 Introduction to Drug Design and Discovery
Chapter 2 Molecular Recognition
Chapter 3 Ligand-Based Drug Design
Chapter 4 Biostructure-Based Drug Design
Chapter 5 Drug-Like Properties and Decision Making in Medicinal Chemistry
Chapter 6 Chemical Biology
Chapter 7 Natural Products in Drug Discovery
Chapter 8 In Vivo Imaging in Drug Discovery
Chapter 9 Peptide and Protein Drug Design
Chapter 10 Prodrugs in Drug Design and Development
Chapter 11 Enzyme Inhibitors: Biostructure- and Mechanism-Based Design
Chapter 12 Receptors: Structure, Function, and Pharmacology
Chapter 13 Ion Channels: Structure and Function
Chapter 14 Neurotransmitter Transporters: Structure, Function, and Drug Binding
Chapter 15 GABA and Glutamic Acid Receptor and Transporter Ligands
Chapter 16 Acetylcholine
Chapter 17 Histamine Receptors
Chapter 18 Dopamine and Serotonin
Chapter 19 Opioid and Cannabinoid Receptors
Chapter 20 Neglected Diseases
Chapter 21 Anticancer Agents
Chapter 22 Targeting Receptor Tyrosine Kinases
Chapter 23 Antibiotics
Index